Karl Fisher titration

Karl Fischer reagents have been used for water determination in analytical laboratories for more than half a century. The original formulation, being based on pyridine became out of favour during the past 30 years due to the accompanying hazard and unpleasant odour. Pyridine-free reagents have therefore increased in popularity and now account for the majority of KF titrations.

It is common practice to calibrate volumetric KF reagents before use against a reference material containing a certified amount of water. Such materials are also available from ROMIL, manufactured from the corresponding Hi‑Dry® anhydrous solvent.